2022
Abatematteo FS, Mosier PD, Niso M, Brunetti L, Berardi F, Loiodice F, Contino M, Delprat B, Maurice T, Laghezza A, Abate C. Development of novel phenoxyalkylpiperidines as high-affinity Sigma-1 receptor ligands with potent anti-amnesic effect. Eur J Med Chem 2022, 228, 114038.
Ayrignac X, Carra-Dallière C, Codjia P, Mouzat K, Castelnovo G, Ellie E, Etcharry-Bouyx F, Belliard S, Marelli C, Portet F, Le Ber I, Durand-Dubief F, Mathey G, Stankoff B, Dorboz I, Drunat S, Boespflug-Tanguy O, Menjot de Champfleur N, Lumbroso S, Mochel F, Labauge P. Evaluation of CSF1R-related adult onset leukoencephalopathy with axonal spheroids and pigmented glia diagnostic criteria. Eur J Neurol. 2022, 29, 329-334.
Bauchet L, Poulen G, Lonjon N, Vachiery-Lahaye F, Bourinet E, Perrin FE, Hugnot JP. Isolation and culture of precursor cells from the adult human spinal cord. Methods Mol Biol. 2022;2389:103-110.
Benkirane M, Da Cunha D, Marelli C, Larrieu L, Renaud M, Varilh J, Pointaux, M, Baux D, Ardouin O, Vangoethem C, Taulan M, Daumas Duport B, Bergougnoux A, Corbillé AG, Cossé M, Juntas Morales R, Tuffery-Giraud S, Koenig M, Isidor B, Vincent MC. RFC1 nonsense and frameshift variants cause CANVAS: clues for an unsolved pathophysiology. Brain 2022, 145, 3770-3775.
Canet G, Zub E, Zussy C, Hernandez C, Blaquiere M, Garcia V, Vitalis M, deBock F, Moreno-Montano M, Audinat E, Desrumaux C, Planel E, Givalois L*, Marchi N*. Seizure activity triggers tau hyperphosphorylation and amyloidogenic pathways. Epilepsia 2022 Apr;63(4):919-935.
Canet G, Zussy C, Hernandez C, Chevallier N, Marchi N, Desrumaux C, Givalois L. Chronic glucocorticoids consumption triggers and worsens experimental Alzheimer’s disease-like pathology by detrimental immune-modulations. Neuroendocrinology 2022, 112, 982-997.
Caporali A, Garcia J, Couppié É, Poniakina S, Barbieri M, Bonnet F, Camarda CG, Cambois E, Hourani I, Korotkova D, Meslé F, Penina O, Robine JM, Sauerberg M, Torres C. The demography of COVID-19 deaths database, a gateway to well-documented international data. Sci Data. 2022 Mar 22;9(1):93.
Carles A, Schlernitzauer A, Vignes M, Cros G, Magous R, Maurice T, Oiry C. Heptafluoroisobutyronitrile (C4F7N), a gas used for insulating and arc quenching in electrical switchgear, is neurotoxic in the mouse brain. Toxicology. 2022, 480, 153319.
Crouzier L, Danese A, Yasui Y, Richard EM, Liévens JC, Patergnani S, Couly S, Diez C, Denus M, Cubedo N, Rossel M, Thiry M, Su TP, Pinton P, Maurice T, Delprat B. Activation of the sigma-1 receptor chaperone alleviates disorders of Wolfram syndrome by restoring ER-mitochondrion signaling. Science Transl Med 2022, 14, 631.
Crouzier L, Richard EM, Diez C, Alzaeem H, Denus M, Cubedo N, Delaunay T, Glendenning E, Baxendale S, Liévens JC, Whitfield TT, Maurice T, Delprat B. Morphological, behavioral and cellular analyses revealed different phenotype in Wolfram syndrome wfs1a and wfs1b zebrafish mutant lines. Hum Mol Genet. 2022, 31, 2711-2727.
Crouzier L, Richard EM, Diez C, Denus M, Peyrel A, Alzaeem H, Cubedo N, Delaunay T, Maurice T, Delprat B. NCS1 overexpression restored mitochondrial activity and behavioral alterations in a zebrafish model of Wolfram syndrome. Mol Therapy, 2022, 27, 295-308.
Hofmann J, Spatz P, Walther R, Gutmann M, Maurice T, Decker M. Synthesis and biological evaluation of flavonoid-cinnamic acid amide hybrids with distinct activity against neurodegeneration in vitro and in vivo. Chem Eur J. 2022, 28, e202200786.
Lasbleiz C, Peyrel A, Tarot P, Sarniguet J, Crouzier L, Cubedo N, Delprat B, Rossel M, Maurice T, Liévens JC. Sigma-1 receptor agonist PRE-084 confers protection against TAR DNA-binding protein-43 toxicity through NRF2 signalling. Redox Biol 2022, 58, 102542.
Lebart MC, Trousse F, Valette G, Torrent J, Denus M, Mestre-Frances N, Marcilhac A. Reg-1α, a New Substrate of Calpain-2 Depending on Its Glycosylation Status. Int J Mol Sci 2022, 23, 8591.
Marcilhac A. Environnement et Vieillissement, partenaires ou adversaires ?” Éditions UGA 2022
Marelli C, Fouilhoux A, Benoist JF, De Lonlay P, Guffon-Fouilhoux N, Brassier A, Cano A, Chabrol B, Pennisi A, Schiff M, Acquaviva C, Murphy E, Servais A, Lachmann R. Very long-term outcomes in 23 patients with cblA type methylmalonic acidemia. J Inherit Metab Dis 2022, 45, 937-951.
Martin P, Maurice T, Gammaitoni A, Farfel G, Boyd B, Galer B. Fenfluramine modulates the anti-amnesic effects induced by sigma-1 receptor agonists and neuro(active)steroids in vivo. Epilepsy Behav, 2022, 127,108526.
Nasri A, Lafon PA, Mezni A, Clair P, Cubedo N, Mahmoudi E, Beyrem H, Rossel M, Perrier V. Developmental exposure to the A6-pesticide causes changes in tyrosine hydroxylase gene expression, neurochemistry, and locomotors behavior in larval zebrafish. Toxicol Mech Methods. 2022, 32, 569-579.
Ramasamy P, Dakshinamoorthy G, Jayashree S, Prabhu D, Rajamanikandan S, Velusamy P, Dayanithi G, Hanna REB. A novel prototype biosensor array electrode system for detecting the bacterial pathogen Salmonella typhimurium. Biosensors (Basel) 2022, 12, 389.
Rochat C, Bernard-Marissal N, Källstig E, Pradervand S, Perrin FE, Aebischer P, Raoul C, Schneider BL. Astrocyte-targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast-fatigable motor units in a mouse model of amyotrophic lateral sclerosis. Glia. 2022, 70, 842-857.
Scheiner M, Sink A, Hoffmann M, Vrigneau C, Endres E, Carles A, Sotriffer C, Maurice T, Decker M. Photoswitchable pseudo-irreversible butyrylcholinesterase inhibitors allow optical control of inhibition in vitro and enable restoration of cognition in an Alzheimer’s disease mouse model upon irradiation. J Am Chem Soc. 2022, 144, 3279-3284.
Seker Yilmaz B, Baruteau J, Arslan N, Aydin HI, Barth M, Bozaci AE, Brassier A, Canda E, Cano A, Chronopoulou E, Connolly GM, Damaj L, Dawson C, Dobbelaere D, Douillard C, Eminoglu FT, Erdol S, Ersoy M, Fang S, Feillet F, Gokcay G, Goksoy E, Gorce M, Inci A, Kadioglu B, Kardas F, Kasapkara CS, Kilic Yildirim G, Kor D, Kose M, Marelli C, Mundy H, O’Sullivan S, Ozturk Hismi B, Ramachandran R, Roubertie A, Sanlilar M, Schiff M, Sreekantam S, Stepien KM, Uzun Unal O, Yildiz Y, Zubarioglu T, Gissen P. Three-country snapshot of ornithine transcarbamylase deficiency. Life (Basel) 2022, 12, 1721.
Spatz P, Zimmermann T, Steinmuller S, Hofmann J, Maurice T, Decker M. Novel benzimidazole-based pseudo-irreversible butyrylcholinesterase inhibitors with neuroprotective activity in an Alzheimer’s disease mouse model. RSC Med Chem 2022, 13, 944-954.
Zussy C, Rijo J, Urgin T, Otaegui L, Vigor C, Acar N, Canet G, Vitalis M, Morin F, Planel E, Oger C, Durand T, Rajshree SL, Givalois L, Devarajan PV, Desrumaux C. Intranasal administration of nanovectorized docosahexaenoic acid (DHA) improves cognitive function in two complementary mouse models of Alzheimer’s disease. Antioxidants 2022, 11, 838.